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Ja'afar, MK, Jamil, S, Basar, N, Bakar, MB, Sarker, SD, Flanagan, KJ and Senge, MO (2017) Lactones and Flavonoids isolated from the Leaves of Globimetula braunii. Natural Product Communications, 12 (9). pp. 1455-1458. ISSN 1934-578X
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Abstract
The dried powdered leaves of Globimetula braunii (Engler) Van Tiegh were effectively extracted by the cold extraction method. Purification of the EtOAc-soluble and MeOH-soluble extracts successfully yielded two lactones namely (R)-6-[(S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]–5,6-dihydropyran-2-one (dodoneine) 1 and (1R,5S,7S)-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]-nonan-3-one (2), together with five flavonoids namely quercetin 3, (+)-catechin 4, quercitrin 5, rutin 6 and avicularin 7. Their structures were established by spectroscopic means, and the absolute configuration of compound 1 was confirmed by X-ray analysis.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 0305 Organic Chemistry, 0607 Plant Biology |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology R Medicine > RV Botanic, Thomsonian, and eclectic medicine |
| Divisions: | Pharmacy and Biomolecular Sciences |
| Publisher: | SAGE Publications |
| Related URLs: | |
| Date of acceptance: | 18 July 2017 |
| Date of first compliant Open Access: | 7 January 2020 |
| Date Deposited: | 07 Jan 2020 09:58 |
| Last Modified: | 04 Sep 2021 10:59 |
| DOI or ID number: | 10.1177/1934578X1701200918 |
| URI: | https://ljmu-9.eprints-hosting.org/id/eprint/7563 |
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