Coenzyme Q10 and Autoimmune Disorders: An Overview

Mantle, D and Hargreaves, IP (2024) Coenzyme Q10 and Autoimmune Disorders: An Overview. International Journal of Molecular Sciences, 25 (8). pp. 1-17. ISSN 1661-6596

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Abstract

Some 90 autoimmune disorders have been described in medical literature, affecting most of the tissues within the body. Autoimmune disorders may be difficult to treat, and there is a need to develop novel therapeutic strategies for these disorders. Autoimmune disorders are characterised by mitochondrial dysfunction, oxidative stress, and inflammation; there is therefore a rationale for a role for coenzyme Q10 in the management of these disorders, on the basis of its key role in normal mitochondrial function, as an antioxidant, and as an anti-inflammatory agent. In this article, we have therefore reviewed the potential role of CoQ10, in terms of both deficiency and/or supplementation, in a range of autoimmune disorders.

Item Type:	Article
Uncontrolled Keywords:	0399 Other Chemical Sciences; 0604 Genetics; 0699 Other Biological Sciences; Chemical Physics
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Pharmacy and Biomolecular Sciences
Publisher:	MDPI
Date of acceptance:	20 April 2022
Date of first compliant Open Access:	23 April 2024
Date Deposited:	23 Apr 2024 10:35
Last Modified:	23 Apr 2024 10:45
DOI or ID number:	10.3390/ijms25084576
URI:	https://ljmu-9.eprints-hosting.org/id/eprint/23126

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