Optimizing adherence and persistence to non-vitamin K antagonist oral anticoagulant therapy in atrial fibrillation

Farinha, JM, Jones, ID and Lip, GYH (2022) Optimizing adherence and persistence to non-vitamin K antagonist oral anticoagulant therapy in atrial fibrillation. European Heart Journal Supplements, 24 (Supple). ISSN 1520-765X

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Abstract

Atrial fibrillation (AF) is associated with an increased risk of stroke, which can be prevented by the use of oral anticoagulation. Although non-vitamin K antagonist oral anticoagulants (NOACs) have become the first choice for stroke prevention in the majority of patients with non-valvular AF, adherence and persistence to these medications remain suboptimal, which may translate into poor health outcomes and increased healthcare costs. Factors influencing adherence and persistence have been suggested to be patient-related, physician-related, and healthcare system-related. In this review, we discuss factors influencing patient adherence and persistence to NOACs and possible problem solving strategies, especially involving an integrated care management, aiming for the improvement in patient outcomes and treatment satisfaction.

Item Type: Article
Uncontrolled Keywords: 1102 Cardiorespiratory Medicine and Haematology
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RT Nursing
Divisions: Nursing and Advanced Practice
Publisher: Oxford University Press (OUP)
Date of acceptance: 5 January 2022
Date of first compliant Open Access: 23 February 2022
Date Deposited: 23 Feb 2022 09:41
Last Modified: 23 Feb 2022 09:45
DOI or ID number: 10.1093/eurheartj/suab152
URI: https://ljmu-9.eprints-hosting.org/id/eprint/16398
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